Sepehr Ehsani

A proposed outline for philosophical biology investigations Source: Figure 1, "A framework for philosophical biology"
The absolute frequency of occurrence of elements 1-118 in cell biology abstracts from 1975 to 2011 Source: Supplementary Figure 3A, "Macro-trends in research on the central dogma of molecular biology"
Timescale of select cellular functions A logarithmic depiction of essential chemical and biological cellular tasks, based on published results, demonstrates a picosecond to second time range. Energy transfer across phospholipid membrane leaflets appears to be a common denominator of slower biological functions. Source: Figure 2, "Time in the cell: a plausible role for the plasma membrane"
A proposed outline for philosophical biology investigations Correlative data captured by a given experiment can be broken down into categories based on the perceived relationship between the cause (A) and the effect (B). 'CE' stands for 'cause-effect'. Source: Figure 1, "Correlative-causative structures and the 'pericause': an analysis of causation and a model based on cellular biology"
Temporality in cause and pericause considerations Source: Ehsani S, unpublished
Distribution of all yeast (Saccharomyces cerevisiae) proteins based on amino acid length Source: Figure 2D, "Identification of the Zeo1 protein as a candidate structural homolog of α-Synuclein in budding yeast"
Balancing act of proteostasis and potential perturbations in neurodegeneration Source: Ehsani S, unpublished
Diagrammatic interpretation of the mammalian prion protein (PrP) interactome Source: Figure 2.9, "The significance of the evolutionary relationship of prion proteins and ZIP transporters in health and disease"
Topological models of PrP and ZIPs 5, 6 and 10, including domain organization and post-translational modifications Source: Figure 1.1B, "The significance of the evolutionary relationship of prion proteins and ZIP transporters in health and disease"
Cartoon comparing properties of ZIP and CDF (ZnT) zinc ion transporters Source: Figure 1.3, "The significance of the evolutionary relationship of prion proteins and ZIP transporters in health and disease"
Natural-logarithm variation of the logistic map representing a continuous model of protein trafficking and degradation Source: Figure 6B, "Simple variation of the logistic map as a model to invoke questions on cellular protein trafficking"

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